Soothing Crossword Clue

The crossword clue "Soothing" with the answer "ANODYNE" refers to something that alleviates pain or provides relief. The term "anodyne" derives from Greek, where "an-" means "without" and "odyne" means "pain."

Thus, "anodyne" literally means "without pain" and is commonly used to describe something that has a calming or soothing effect. In crossword puzzles, clues that use "soothing" to describe the answer "anodyne" are drawing on this medical and figurative sense, indicating that the answer represents something that eases discomfort or offers a gentle remedy.

The crossword clue "Soothing" with the answer "AZOTIZE" refers to a chemical process involving the addition of nitrogen to a compound, often used in historical contexts.

The term "azotize" is derived from "azote," an old name for nitrogen, combined with the suffix "-ize," indicating a process or action. 

The crossword clue "Soothing" with the answer "APPRIZE" refers to a situation where the term "apprize" means to inform or give notice, which can be metaphorically linked to soothing or calming someone by providing important information or reassurance.

In a broader sense, when you apprize someone, you make them aware of something, which can alleviate uncertainty or anxiety, thus having a soothing effect. 

The crossword clue "Soothing" with the answer "ACQHIRE" refers to a specific term in a nuanced and playful use of language. In this context, "ACQHIRE" is a portmanteau of "acquire" and "hire," which creatively blends two actions that can be related to calming or easing a situation.

While not a standard word, it hints at a process of gaining or bringing on board something that could potentially provide relief or comfort, akin to soothing.